MBS, is a heterobifunctional amine to sulfhydryl crosslinking reagent.
MBS contains one NHS ester group and a maleimide reactive group at each end of a small aromatic spacer.
The sulfo-NHS ester groups readily react towards primary amines at pH 7-9.
The maleimide group reacts towards sulfhydryl (or thiol) groups at pH 6.5-7.5.
MBS is not water soluble and must be dissolved in an organic solvent such as DMSO or DMF prior to use.


Water-insoluble and non cleavable

3-Maleimidobenzoic acid N-hydroxysuccinimide ester, m-maleimidobenzoyl-N-hydroxysuccinimide ester


314.30 g/mol

175-177 °C

Desiccated at -20 °C under Argon. Product is shipped at ambient temperature

≥ 99%


DMSO, DMF. Water insoluble

Order guide

Order-No.Unit SizePrice
E020W,005050 mg65.00
E020W,0100100 mg100.00
E020W,0250250 mg180.00

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